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Tru Niagen Review: How Well Does It Actually Promote Healthy Aging?

John Joshua

Let’s talk about something called nicotinamide adenine dinucleotide. We can stick with “NAD”, for short. This cellular ingredient declines with age and plays a major role in cell repair, cognitive function and metabolism. Is there a way to recover these cellular health benefits despite the aging process?
This anti aging supplement claims to do that. Tru Niagen Nicotinamide Riboside contains the one ingredient that might raise NAD levels, which may offer benefits like better energy.

What Is Tru Niagen?


Tru Niagen, by ChromaDex, is a healthy energy product that may help you defy aging by reinvigorating cellular growth and repair. It does this by raising your NAD levels.
Research shows that NAD helps your body turn nutrients and food into energy, boosting metabolism [1]. It also plays a role in neuron communication and muscle contraction and relaxation, to name a few.
These health functions become challenging as you age, so it’s possible that a daily NAD boost may provide positive effects for you. With your cells in good shape, there’s a chance that Tru Niagen could also help you avoid age-related diseases such as dementia and Alzheimer’s.
Tru Niagen might be for you if you’re an older adult who’s concerned about the aging process and your health as it happens. It’s free of allergens, vegetarian-friendly, caffeine free, gluten free and contains no artificial flavors or colors.

Are There Any Side Effects?

Our research leads us to believe that the health side effects of taking Tru Niagen to elevate NAD levels are substantially fewer than many other supplements on the market.
You could experience the following month to month, in mild-to-moderate settings:

  • Headache
  • Indigestion
  • Diarrhea
  • Fatigue
  • Nausea
  • Stomach
  • discomfort

As with any other supplement, we recommend that you study the facts and consult with a certified physician or trusted doctor before taking Tru Niagen for NAD.

How Does Tru Niagen Work?

ChromaDex keeps things simple with this health supplement that’s backed by clinical trials. Tru Niagen contains only one ingredient.

Niagen (Nicotinamide Riboside Chloride) – 150 milligrams or 300 milligrams

Nicotinamide riboside nr, a NAD precursor, belongs to the family of Vitamin B3 substances.
In nature, you can find this ingredient in poultry products, beef liver, turkey, pork and various seafoods including salmon and anchovies. Vegetarian sources include avocado, peanuts and green peas, among others.
But how does it function in the body? According to research, your body converts this vitamin into NAD, which is described as a “helper molecule” [2]. This indicates that it is a strong participant in various processes, which include:

  • Repairing damaged DNA
  • Turning food into energy
  • Strengthening the cell’s defense mechanisms
  • Setting the body’s circadian rhythms, or natural sleep patterns

Like many other helper chemicals, niagen decreases naturally as you age, which means the processes it participates in could suffer.

Benefits of Niagen

Is this anti aging supplement all it’s cracked up to be? It may not prevent any disease, but here are the possible benefits of taking Tru Niagen:

  • Protects Brain Cells

NAD plays a role in managing production of a protein called “PGC-1-Alpha”. This protein helps the body fight against oxidative stress, which happens as you get older [3]. It’s linked to diseases such as Alzheimer’s and Parkinsons.
This could potentially lead to a sharper mind and more energy.

  • Converts to NAD Successfully

It’s shown that nicotinamide riboside converts to NAD easily, indicating that a high level of bioavailability is linked to ease of use in the human body [4].
There’s a possibility that supplementing with Tru Niagen may raise NAD blood levels by at least 2.7 times, as noted in the study.

  • Improves Cardiovascular Function

Research shows that nicotinamide riboside supplementation might help lower blood pressure and aortic stiffness, both side effects of age and potentially dangerous for the heart [5].

  • Lowers Cancer Risks

Some studies show that Tru Niagen might also help lower your risk for specific cancers including liver cancer, since it helps fight oxidative stress and DNA damage, which happens with age [6].

  • Improves Age-Related Enzyme Functioning

Enzymes are protein molecules that speed up the functioning, actions and reactions of your cells. Specific enzymes, like sirtuins, decrease with age. They play a role in reducing stress, inflammation and repairing DNA.
Studies show that nicotinamide riboside may improve the functioning of such enzymes to promote a healthy aging process [7].

Tru Niagen 150 milligrams vs 300 milligrams

Tru Niagen is available in two different doses, 150 milligrams or 300 milligrams.
ChromaDex makes it clear on its official company website that the recommended dosage is 300 mg per day each month.
The only reason for the 150 mg option is because it’s packaged in a smaller capsule size for those that have difficulty swallowing large pills. In this case, you would take two per day versus one 300 milligram pill.
The company also offers Tru Niagen Stickpacks, consisting of a powder form that you can mix into liquid and drink.

How Should I Take Tru Niagen?

Niagen is a straightforward health supplement and made for use every day.

What Is the Daily Dosage?

ChromaDex recommends that each adult takes 300 mg per day, preferably in the morning.
However, if you choose the 150 mg pills, you can take one in the morning and one later in the day, or both together in the morning. Your preference.

What Happens If I Miss a Dose?

There’s not a single study on this, but one of the upsides of taking a natural supplement for energy is that missing a dose isn’t a big deal.
We don’t recommend two doses at once, though, because this could lead to an upset stomach or any of the other side effects listed earlier in the review.
Instead, wait until your next dose and continue on that way. Track your intake each month and keep a solid routine to avoid confusion.

Can I Take More for Faster Results?

Taking more Niagen to increase NAD for faster results won’t exactly bring about the benefits you’re looking for.
In fact, it could cause negative side effects. Your body can only absorb so much at once, so we recommend sticking with the manufacturer’s instructions.

When Should I Not Take Niagen?

As far as we can tell, there isn’t anyone who shouldn’t try Niagen for health. It’s approved by the Food and Drug Administration (FDA) and is deemed a safe supplement.
With that said, it’s always recommended to speak with a medical professional before taking a new product. This is especially the case if you have any preexisting condition or are pregnant.

How Long Should I Take It For?

Niagen itself doesn’t pose harm with long term use, nor is there a study that says otherwise. Given that Tru Niagen only contains this single product for NAD, you should be able to take it for as long as you see benefits.
It might take up to two months for it to work.

Is Tru Niagen Worth It?

Based on the groundbreaking research and each study behind this supplement and how it might affect NAD levels, it could be worth looking into if cellular age is important to you.
While these health product capsules do cost, Tru Niagen is more budget-friendly than many anti aging product options available on the market today. You can purchase a 1 month, 3 months or 6 months supply with a chance to save costs if you buy in bulk.
Order yours once per month or enroll in the ChromaDex automatic delivery system where yours are delivered on a per month basis automatically.
Do keep in mind that this drug for raising your nicotinamide adenine dinucleotide levels is evaluated by the Food and Drug administration (FDA) as being safe. However, the FDA hasn’t cleared the claims associated with the product on the ChromaDex website, even though some studies back it up.

Does Tru Niagen Have a Money Back Guarantee?

ChromaDex does offer a money back guarantee within 30 days. However, it’s important to note this is on bottles that you haven’t opened.
If you choose to start taking Tru Niagen for NAD and decide to forego the remainder of a bottle, the cost will be on you. A bottle is around $50 for a one time purchase to give you an idea.

Tru Niagen Review in Conclusion

In our review of this FDA approved anti aging dietary supplement for increasing NAD levels, we can determine that there may be cellular health benefits if you take it. Leading scientists like Charles Brenner would most certainly agree.
There are only a few clinical studies linking Tru Niagen to an uptick in NAD nicotinamide, however, they do exist. Furthermore, study after study points to the importance of NAD in the body.
Given that this product contains a NAD precursor, there’s a high chance it does what the ChromaDex company claims. You’ll also find plenty of customer reviews laying claim to more obvious effects like sound sleep and energy production.
Nicotinamide adenine dinucleotide NAD declines as you age and the metabolic stress associated with it might be reason enough to try one of the products. It’s only a form of vitamin B3, so there’s little harm.

References

1. Martens CR;Denman BA;Mazzo MR;Armstrong ML;Reisdorph N;McQueen MB;Chonchol M;Seals DR; “Chronic Nicotinamide Riboside Supplementation Is Well-Tolerated and Elevates NAD + in Healthy Middle-Aged and Older Adults.” Nature Communications, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/29599478/.

2. SI;, Johnson S;Imai. “NAD + Biosynthesis, Aging, and Disease.” F1000Research, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/29744033/.

3. J;, Sweeney G;Song. “The Association between PGC-1α and Alzheimer’s Disease.” Anatomy & Cell Biology, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/27051562/.

4. Trammell SA;Schmidt MS;Weidemann BJ;Redpath P;Jaksch F;Dellinger RW;Li Z;Abel ED;Migaud ME;Brenner C; “Nicotinamide Riboside Is Uniquely and Orally Bioavailable in Mice and Humans.” Nature Communications, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/27721479/.

5. Martens, Christopher, et al. “Nicotinamide Riboside Supplementation Reduces Aortic Stiffness and Blood Pressure in Middle-Aged and Older Adults.” Artery Research, No Longer Published by Elsevier, 6 Dec. 2017, www.sciencedirect.com/science/article/abs/pii/S1872931217301011.

6. N;, Djouder. “Boosting NAD(+) for the Prevention and Treatment of Liver Cancer.” Molecular & Cellular Oncology, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/27308492/.

7. S;, Satoh A;Stein L;Imai. “The Role of Mammalian Sirtuins in the Regulation of Metabolism, Aging, and Longevity.” Handbook of Experimental Pharmacology, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/21879449/.

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